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Clinical Efficacy of a New Mouthwash Containing Essential Oil of Cardamom in Reducing Volatile Sulphur Coumpounds Concentration
Int J Clin Prev Dent 2014;10(4):237-242
Published online December 30, 2014
© 2014 International Journal of Clinical Preventive Dentistry.

Suci Erawati1, Anton Rahardjo2, Sondang Pintauli3

1Doctoral Student, Graduate School of Faculty of Dentistry, University of Sumatera Utara, Medan, 2Department of Preventive Dentistry, Faculty of Dentistry, University of Indonesia, Jakarta, 3Department of Preventive Dentistry, Faculty of Dentistry, University of Sumatera Utara, Medan, Indonesia
Correspondence to: Anton Rahardjo
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Objective: The aim of this study was to assess the clinical efficacy of new mouthwash based on kapulaga fruit (Amomum cardamommum L.) containing 0.5% essential oil and compared to 0.5% Listerine? as a positive control and placebo in reducing volatile sulphur compounds (VSCs) concentration of halitosis subjects. Methods: A randomized, double blinded, cross-over design was conducted among 20 healthy volunteers in Medan, Indonesia. Subjects were divided into 3 groups (Cardamom, Listerine?, placebo group) and instructed to rinse 10 ml of experiment
and control mouthwash twice per day for 5 days. After one week washout periods, each group used the opposite mouthwash. The concentration of VSCs, hydrogen sulfide, methyl mercaptan, and dimethyl sulfide were assessed twice daily for 5 days (morning at 5 a.m. and afternoon at 11 a.m.) by using oral chroma and organoleptic measurement. The three mouthwash were analyzed statistically by repeated measures ANOVA. Results: Either Cardamom or Listerine? was effective in reducing VSCs for up to 4 to 5 hours after mouth rinsing, while placebo not. An analysis showed significant differences of cardamom essential oil in mouthwash and positive control group
(p<0.05) from 1st and 5th day while no significant difference in placebo group (p>0.05). Results showed that Cardamom more effective than the other two mouthwashes. Unlike other mouthwash in general, the advantage of cardamom essential oil in mouthwash is alcohol-free, that could avoid from oral pain and sensitivity. Conclusion: It can be concluded that 0.5% cardamom containing essential oil in mouthwash is useful to overcome halitosis.
Keywords : essential oils, volatile oils, halitosis
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