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The Interdental Cleansing, Stain Removing and Calculus Deposit Inhibition Effect of Toothpaste Containing Tetrasodium Pyrophosphate and Soft Granule (Zeolite-M)
International Journal of Clinical Preventive Dentistry 2013;9(4):199-206
Published online December 30, 2013
© 2013 International Journal of Clinical Preventive Dentistry.

Won-Ho Ha1, Jae-Hyun Ahn1, A-Ram You1, Ji-Hye Kim1, Min-Jeong Cho2, Seung-Chul Shin3
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Objective: The purpose of this study was to investigate the stain removal, calculus deposit inhibition, and cleaning effect for teeth surface and interdental region by using toothpaste containing Pyrophosphate and soft granule (Zeolite-M).Methods: 1) For the study, general toothpaste was prepared as control and 2 kinds of test toothpastes were prepared. Test toothpaste-1(T1) containing Pyrophosphate and test toothpaste-2 (T2) containing Pyrophosphate and soft granule (Zeolite-M, Ultra White Ball). 2) In-vitro study: The stain removal and interdental cleaning effect were measured using stained Hydroxyapatite tablet, and 20 subjects’ teeth surface and interdental cleaning effect by brushing was evaluated with test toothpaste. 3) Clinical study: The study was performed on 88 subjects. Calculus index and Stain index were measured during 8 week. Results: 1) T2 showed the highest stain removal and cleaning effect for teeth surface and interdental region. The results of the experiment were statistically significant (p<0.05). 2) After using toothpastes 4 weeks, subjects using T2 showed less tartar deposit than using control, and after 8 weeks, T2 statistically inhibit tartar formation than T1 and control (p<0.05). 3) Using T2 longer than 4 weeks could be accepted as a highly effective way to stain removal.Conclusion: T2 showed significantly effective on plaque, stain removal, calculus deposit inhibition and cleaning for teeth surface and interdental region than control toothpastes. Therefore, toothpaste containing pyrophosphate and soft granule is recommendable to prevent calculus formation and teeth staining. The subjects using T 2 can feel whitening efficacy and sat-isfaction of cleaning more than placebo and T1.
Keywords : calculus deposit inhibition, interdental cleaning, stain removal, tetrasodium pyrophosphate, Zeolite-M

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