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Halitosis Reduction Effect of a Natural Extract-Containing Toothpaste In Vivo
Int J Clin Prev Dent 2019;15(4):183-187
Published online December 31, 2019;  https://doi.org/10.15236/ijcpd.2019.15.4.183
© 2019 International Journal of Clinical Preventive Dentistry.

Ji-Young Lee1, Inchul Hwang2, Se-Hyun Hwang1

1Department of Dental Hygiene, Dongju College, 2Department of Health Sciences, Graduate School, Kosin University, Busan, Korea
Correspondence to: Inchul Hwang
E-mail: hwang@kosin.ac.kr
https://orcid.org/0000-0002-1664-9854
Received November 30, 2019; Revised December 19, 2019; Accepted December 30, 2019.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Objectives: Compositions extracted from 31 kinds of natural materials were prepared and formulated with toothpaste ingredients (e.g., cleaning, polishing, flavoring), to evaluate the halitosis reduction effect compared to a commercial toothpaste.
Methods: This research was performed between May and June, 2019 with 30 females over 20 years of age. Assessments of halitosis were conducted before brushing teeth, and 30 minutes and 3 hours after brushing using a natural extract-containing dentifrice (experimental group) and a commercial dentifrice (positive control group).
Results: The average values of halitosis measurements decreased significantly over time (F=133.087, p=0.000); values in the experimental and control groups, respectively were: 32.6±17.5 vs. 34.3±14.2 (pre-brushing), 10.6±8.7 vs. 16.2±10.3 (30 min post-brushing) and 4.6±6.9 vs. 5.5±8.8 (3 h post-brushing). No differences were exhibited between the groups (F=1.583, p=0.213) and between the groups and time (F=1.020, p=0.364).
Conclusions: The natural extract-containing dentifrice was more effective at reducing halitosis 30 minutes after brushing compared to a commercial dentifrice, however, the effect was similar among the groups 3 hours after brushing, and this effect was maintained consistently over time. The natural extract-containing dentifrice developed in this study is expected to be: i) safe for use long-term use (i.e., no side effects) and ii) an appropriate dentifrice for reducing halitosis.
Keywords : natural extract, oral malodor, dentifrice, toothpaste, halitosis
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December 2019, 15 (4)