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The Effect of a Natural Extracts-Containing Toothpaste on Dental Plaque Reduction in vivo
Int J Clin Prev Dent 2019;15(3):168-172
Published online September 30, 2019;
© 2019 International Journal of Clinical Preventive Dentistry.

Ji-Young Lee1, Inchul Hwang2

1Department of Dental Hygiene, Dongju College, 2Department of Health Sciences, Graduate School, Kosin University, Busan, Korea
Correspondence to: Inchul Hwang
Received September 2, 2019; Revised September 20, 2019; Accepted September 24, 2019.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Objective: A dentifrice formulated with natural extracts effective at reducing plaque was developed and its ability to control dental plaque was compared to an existing product with high market share (positive control). Assessments were made using the modified patient hygiene performance (m-PHP) index, i.e., oral environmental management capability index.

Methods: Dental plaque tests were performed on 30 female students over 20 years of age before, thirty minutes after and three hours after brushing teeth with a natural extract-containing dentifrice and a control product.

Results: The mean m-PHP indices of the experimental and control groups, respectively were 70.4±11.1 and 60.8±11.8 (before brushing teeth), 90.6±8.1 and 83.3±6.6 (30 minutes after brushing), and 88.6±8.8 and 80.7±6.7 (three hours after brushing). Repeated-measure ANOVA revealed significant differences between time (F=474.233, p=0.000), and between groups (F=14.582, p=0.000), but not between groups and time (F=1.336, p=0.267). Comparing only before brushing and 30 minutes after brushing teeth, it was found that the oral environmental management capacity of the experimental group was better compared with the control group (time: F=503.5, p=0.000; between groups: F=13.615, p=0.000; between groups and time: F=1.583, p=0.213).

Conclusion: The dental plaque-reduction capacity of this novel dentifrice containing natural extracts was significantly superior to that of an existing product with high market share.
Keywords : natural extract, dentifrice, plaque reduction, dental plaque index, toothpaste
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