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Comparative Study of Two Different Collagen Membranes in the Treatment of Periodontal Defects: a Randomized Clinical Trial
Int J Clin Prev Dent 2019;15(3):121-128
Published online September 30, 2019;  https://doi.org/10.15236/ijcpd.2019.15.3.121
© 2019 International Journal of Clinical Preventive Dentistry.

Eunsuk Cho1, Kiseok Hong2

1Mohyun Samsung Dental Clinic, Iksan, 2Moon Dental Hospital, Cheonan, Korea
Correspondence to: Kiseok Hong
E-mail: periohong@gmail.com
https://orcid.org/0000-0002-8308-585X
Received September 22, 2019; Revised September 23, 2019; Accepted September 24, 2019.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Objective: The purpose of this comparative study is to assess the clinical, radiographic outcomes of guided tissue regeneration (GTR) with non-crosslinked and bio-crosslinked collagen membranes, in combination with bovine bone mineral (BBM) graft.

Methods: The control group was treated only with BBM (n=10), test group I was treated with non-crosslinked collagen membrane and BBM (n=10), and test group II was treated with bio-crosslinked collagen membrane and BBM (n=10). The measurement of clinical parameters and radiographic evaluation were done before surgery and 3 months after surgery. Clinical parameters measured were plaque index (PI), gingival index (GI), probing depth (PD) and clinical attachment level (CAL).

Results: Three months after surgery, all three groups showed marked improvement in PD and CAL with statistical significance. None of the groups showed significant improvement in PI and only the test group II showed significant improvement in GI within 0.01 level. The mean reduction in PD was 2.6 mm for the control group, 3.8 mm for the test group I, 3.2 mm for the test group II. The mean improvement in CAL was 2.3 mm for the control group, 3.3 mm for the test group I, 3.2 mm for the test group II. Radiographic evaluation revealed two barrier groups over 40% bone fill while BBM group showed only 29.9% bone fill.

Conclusion: The present study demonstrated that both collagen membranes were beneficial for the treatment of intrabony defects.
Keywords : guided tissue regeneration, bone, crosslinking, collagen, membrane
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September 2019, 15 (3)