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A Clinical Test of Dental Hypersensitivity by Use of the Dentifrice with the Desensitization Agents
Int J Clin Prev Dent 2018;14(1):29-34
Published online March 31, 2018;
© 2018 International Journal of Clinical Preventive Dentistry.

Jin-Hee Won1, Su-Ok Lee1, Mi-Ra Lee2, Su-Yeon Park3

1Department of Dental Hygiene, Chungbuk Health & Science University, Cheongju, 2Department of Dental Hygiene, Baekseok Culture University, 3GAON Dental Hospital, Cheonan, Korea
Correspondence to: Su-Yeon Park
GAON Dental Hospital, 129 Dongseo-daero, Seobuk-gu, Cheonan 31109, Korea. 
Tel: +82-42-552-0005, Fax: +82-2- 6280-2468, E-mail:
Received March 20, 2018; Revised March 25, 2018; Accepted March 25, 2018.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Objective: In order to examine the desensitization effect for the dentifrice with such ingredient as Zinc Chloride and Kalium Phosphate 1 and 2, by the experiment in vitro and in vivo.Methods: Ninety-nine adults volunteers who had a little hyper-sensitive dentin were divided with 3 groups as experimental, negative or positive control group, after in vitro experiment as closing ability for dentinal tubules by use of each dentifrice, and observed them with scanning electro microscope (SEM). Clinical test for desensitization effect was checked by use of electric pulp tester after using each dentifrice contained Zinc Chloride or Kalium Phosphate. Questionnaire method was added in order to check the subject’s response for satisfaction.Results: More closing effect on the dentinal tubules with the precipitation materials through coagulation of protein by were seen in experimental group than in negative or positive control group, observed with SEM in vitro study. The most in experimental group were satisfied to use the dentifrice with desensitization ingredients, examined by questionnaire method (p<0.05). It revealed more leveled in Electro-Pulp test in experimental group than in negative or positive control group for hypersensitivity check for 6 days use (p<0.05).Conclusion: Dentifrice with Zinc Chloride and Kalium Phosphate together was recommended to use for hypersensitivity dental patient.
Keywords : dentin hypersensitivity, dentin desensitizing agents, toothpastes
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December 2018, 14 (4)