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A Study on the Evaluation of Oral Malodor Reduction Effect of Zinc Citrate-Containing Dentifrice on Night Use
Int J Clin Prev Dent 2018;14(1):23-28
Published online March 31, 2018;
© 2018 International Journal of Clinical Preventive Dentistry.

Eun-Joo Na1, Mi-Hae Yun1, Ja-Won Cho2

1Department of Dental Hygiene, Daejeon Health Institute of Technology, Daejeon, 2Department of Preventive Dentistry, College of Dentistry, Dankook University, Cheonan, Korea
Correspondence to: Ja-Won Cho
Department of Preventive Dentistry, College of Dentistry, Dankook University, 119 Dandae-ro, Dongnam-gu, Cheonan31116, Korea. Tel: +82-41-550-1953, Fax: +82-41-553- 6582, E-mail:
Received January 19, 2018; Revised February 28, 2018; Accepted March 2, 2018.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Objective: This study was conducted to confirm the oral malodor reduction effect of zinc citrate-containing dentifrice on night use.Methods: This study was designed as a parallel, randomized, double-blind, and control trial for 3 weeks. After 1-week run-in period, the subjects were randomly assigned to the experimental groups (zinc-citrate-containing-dentifrice using group) or the control group. After 3 days, 5 days, 1 week, 2 weeks, and 3 weeks, oral malodors were measured and compared.Results: As a result of measurement of volatile sulfur compounds using Oralchroma, before the experiment, the experimental group 3.01 ng/10 ml and the control group 3.03 ng/10 ml, after 3 days, 2.77 ng/10 ml, 3.01 ng/10 ml, after 5 days, 2.67 ng/10 ml, 2.95 ng/10 ml, after one week, 2.62 ng/10 ml, 2.96 ng/10 ml, and decreased to 2.50 ng/10 ml and 2.92 ng/10 ml after 2 weeks.Conclusion: In case of using the dentifrice for the oral malodor using zinc citrate once before sleeping, It was confirmed that the effective and quick oral malodor reduction effect can be expected compared with the existing dentifrice.
Keywords : oral malodor, zinc citrate-containing dentifrice

March 2018, 14 (1)