search for




 

A Study on Evaluation of Effect of Mitigating Dentin Hypersensitivity of Dentifrice Containing Potassium Nitrate (KNO3:101.10) and Aluminum Lactate(C9H15AIO9:294.19)
Int J Clin Prev Dent 2017;13(4):189-196
Published online December 31, 2017;  https://doi.org/10.15236/ijcpd.2017.13.4.189
© 2017 International Journal of Clinical Preventive Dentistry.

Soo-Young Lee1, Cheon-Hee Lee2, Yong-Duk Park3, Jee-Hyeon Shim1, Ja-Won Cho4

1Department of Oral and Health, Graduate School of Health and Welfare, Dankook University, Cheonan, 2Department of Dental Hygiene, Andong Science College, Andong, 3Department of Preventive Dentistry, School of Dentistry, Chosun University, Gwangju, 4Department of Preventive Dentistry, College of Dentistry, Dankook University, Cheonan, Korea
Correspondence to: Ja-Won Cho
Department of Preventive Dentistry, College of Dentistry, Dankook University, 119 Dandae-ro, Dongnam-gu, Cheonan 31116, Korea. Tel: +82-41-550-1953, Fax: +82-41-553-6582, E-mail: priscus @dku.edu
Received December 9, 2017; Revised December 20, 2017; Accepted December 20, 2017.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Objective: To identify whether dentifrice containing two ingredients of potassium nitrate and aluminum lactate has mitigating effect on dentin hypersensitivity. Methods: The study dentifrice contained potassium nitrate and aluminum lactate, and standard dentifrice was a usual dentifrice with dental type silica as the main ingredient containing sodium monofluorophosphate. The degree of dentin hypersensitivity was measured at the base, after 3 days, 1 week, 2 weeks, 4 weeks, 4 weeks+3 days, and 6 weeks. The results were compared. Results: There was a significant difference (p<0.01) in the electrodermal stimulation test between the experimental group and the control group using the 6-week treatment, and after the 4-week application of the corrective agent (p<0.05). There was no significant difference between the two groups (p<0.05) and 4 weeks (p<0.01) in the case of wind stimulation test, and 3 days (p<0.01) in the additional experiment using standard detergent after 4 weeks At 2 weeks (p<0.05), significant teeth appeared. in cold stimulation test, there was a significant difference at 2 weeks (p<0.05) and 4 weeks (p<0.01), and 2 weeks respectively (p<0.05).Conclusion: It was found that the use of dentifrice containing potassium nitrate and aluminum lactate was effective in reducing the dentin hypersensitivity. 
Keywords : potassium nitrate, aluminum lactate, dentin sensitivity, dentifrices
References
  1. Rauschenberger CR. Dentin permeability. The clinical ramifications. Dent Clin North Am 1992;36:527-42.
    Pubmed
  2. Jacobsen PL, Bruce G. Clinical dentin hypersensitivity: understanding the causes and prescribing a treatment. J Contemp Dent Pract 2001;2:1-12.
    Pubmed
  3. Brännström M, Aström A. The hydrodynamics of the dentine; its possible relationship to dentinal pain. Int Dent J 1972;22:219- 27.
    Pubmed
  4. Yoshiyama M, Suge T, Kawasaki A, Ebisu S. Morphological characterization of tube-like structures in hypersensitive human radicular dentine. J Dent 1996;24:57-63.
    CrossRef
  5. Kim JH, Kim SU, Kwon YH, Lee MS. Clinical evaluation of microcrystalline hydroxyapatite toothpaste in the control of dentin hypersensitivity. J Korean Acad Periodontol 1984;14:229-40.
  6. B Low S, Allen EP, Kontogiorgos ED. Reduction in dental hypersensitivity with nano-hydroxyapatite, potassium nitrate, sodium monoflurophosphate and antioxidants. Open Dent J 2015; (9):92-7.
    Pubmed
  7. Satyapal T, Mali R, Mali A, Patil V. Comparative evaluation of a dentifrice containing calcium sodium phosphosilicate to a dentifrice containing potassium nitrate for dentinal hypersensitivity: a clinical study. J Indian Soc Periodontol 2014;18: 581-5.
    Pubmed CrossRef
  8. Kim S. Hypersensitive teeth: desensitization of pulpal sensory nerves. J Endod 1986;12:482-5.
    CrossRef
  9. Tarbet WJ, Silverman G, Fratarcangelo PA, Kanapka JA. Home treatment for dentinal hypersensitivity: a comparative study. J Am Dent Assoc 1982;105:227-30.
    Pubmed CrossRef
  10. Nagata T, Ishida H, Shinohara H, Nishikawa S, Kasahara S, Wakano Y, et al. Clinical evaluation of a potassium nitrate dentifrice for the treatment of dentinal hypersensitivity. J Clin Periodontol 1994;21:217-21.
    Pubmed CrossRef
  11. Lee SY. Occlusion effect of dentinal tubules of the desensitizing dentifrices marketed in Korea. J Dent Hyg Sci 2011;11:431-6.
  12. Peacock JM, Orchardson R. Effects of potassium ions on action potential conduction in A- and C-fibers of rat spinal nerves. J Dent Res 1995;74:634-41.
    Pubmed CrossRef
  13. Higuchi Y, Kurihara H, Nishimura F, Miyamoto M, Arai H, Nakagawa M, et al. Clinical evaluation of a dental rinse containing aluminum lactate for treatment of dentinal hypersensitivity. J Clin Dent 1996;7:9-12.
    Pubmed
  14. Kim YS. Evaluation of Electric Pulp Test (EPT) as a tool for measurement of dentinal hypersensitivity. J Periodontal Implant Sci 2002;32:371-8.
    CrossRef
  15. Orchardson R, Gillam DG. Managing dentin hypersensitivity. J Am Dent Assoc 2006;137:990-8; quiz 1028-9.
    Pubmed CrossRef
  16. Hong MH, Kim YS. A study on periodontal disease awareness and periodontal health status among industrial workers. J Korea Contents Assoc 2009;9:216-24.
    CrossRef
  17. Swift EJ Jr. Causes, prevention, and treatment of dentin hypersensitivity. Compend Contin Educ Dent 2004;25:95-106, 109; quiz 110.
  18. Song DH, Kim JY, Jeong JH. The SEM observation of the sealing effect on denuded dentinal tubules after application of desensitizing agent containing dentifrices. J Dankook Dent Res Inst 1995;7:55-63.
  19. Absi EG, Addy M, Adams D. Dentine hypersensitivity. A study of the patency of dentinal tubules in sensitive and non-sensitive cervical dentine. J Clin Periodontol 1987;14:280-4.
    Pubmed CrossRef
  20. Pashley DH, Livingston MJ, Greenhill JD. Regional resistances to fluid flow in human dentine in vitro. Arch Oral Biol 1978;23:807-10.
    CrossRef
  21. Kim NH, Mun SJ, Kim AH, Min JH, Ahn JH, Ha WH, et al. The antimicrobial and anti-plaque effect of dentifrice containing baking soda and triclosan. J Korean Acad Oral Health 2011;35: 10-7.
    CrossRef
  22. Addy M. Etiology and clinical implications of dentine hypersensitivity. Dent Clin North Am 1990;34:503-14.
    Pubmed
  23. Wara-aswapati N, Krongnawakul D, Jiraviboon D, Adulyanon S, Karimbux N, Pitiphat W. The effect of a new toothpaste containing potassium nitrate and triclosan on gingival health, plaque formation and dentine hypersensitivity. J Clin Periodontol 2005;32:53-8.
    Pubmed CrossRef
  24. Schiff T, Dotson M, Cohen S, De Vizio W, McCool J, Volpe A. Efficacy of a dentifrice containing potassium nitrate, soluble pyrophosphate, PVM/MA copolymer, and sodium fluoride on dentinal hypersensitivity: a twelve-week clinical study. J Clin Dent 1994;5 Spec No:87-92.
    Pubmed
  25. Arrais CA, Micheloni CD, Giannini M, Chan DC. Occluding effect of dentifrices on dentinal tubules. J Dent 2003;31:577-84.
    CrossRef
  26. Hong JY, Lim HC, Herr Y. Effects of a mouthwash containing potassium nitrate, sodium fluoride, and cetylpyridinium chloride on dentin hypersensitivity: a randomized, double-blind, placebo-controlled study. J Periodontal Implant Sci 2016;46:46- 56.
    Pubmed CrossRef
  27. Gillam DG, Newman HN, Bulman JS, Davies EH. Dentifrice abrasivity and cervical dentinal hypersensitivity. Results 12 weeks following cessation of 8 weeks’ supervised use. J Periodontol 1992;63:7-12.
    Pubmed CrossRef
  28. Addy M, Mostafa P, Newcombe R. Dentin hypersensitivity: a comparison of five toothpastes used during a 6-week treatment period. Br Dent J 1987;163:45-51.
    Pubmed CrossRef
  29. Liu H, Hu D. Efficacy of a commercial dentifrice containing 2% strontium chloride and 5% potassium nitrate for dentin hypersensitivity: a 3-day clinical study in adults in China. Clin Ther 2012;34:614-22.
    Pubmed CrossRef
  30. Sharma S, Shetty NJ, Uppoor A. Evaluation of the clinical efficacy of potassium nitrate desensitizing mouthwash and a toothpaste in the treatment of dentinal hypersensitivity. J Clin Exp Dent 2012;4:e28-33.
    Pubmed CrossRef
  31. Zhuang WJ, Cao D. Efficacy of a dentifrice containing 5% potassium nitrate on dental hypersensitivity. Shanghai Kou Qiang Yi Xue 2011;20:638-40.
    Pubmed
  32. Wang Y, Gao J, Jiang T, Liang S, Zhou Y, Matis BA. Evaluation of the efficacy of potassium nitrate and sodium fluoride as desensitizing agents during tooth bleaching treatment: a systematic review and meta-analysis. J Dent 2015;43:913-23.
    Pubmed CrossRef
  33. Kim JS, Lim JH, Park HJ. The closure effect of the dental tubules by use of dentifrice with the desensitization agent. Int J Clin Prev Dent 2016;12:121-6.
    CrossRef


March 2018, 14 (1)